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Product Information

Ziprasidone

This program is the subject of a licensing agreement with Meiji Seika Pharma, Co., Ltd. For details, please see the Licensing Status link.


Class Second generation (atypical) anti-psychotic
Mechanism of Action D2 and 5-HT2A antagonist
Target Indication Schizophrenia, Bipolar Disorder
Overseas Development Status Marketed (Geodon)
Portfolio for development and marketing rights in Japan
Product Summary

Schizophrenia is a mental disorder which commonly manifests itself via hallucinations, paranoia and various other symptoms, and affects approximately one percent of the world’s population. Ziprasidone is an atypical antipsychotic drug and demonstrates antagonistic efficacy both on the dopamine D2 receptor and serotonin 5-HT2A receptor. Ziprasidone has some advantages over other currently available second generation antipsychotic drugs, including a low risk of body weight gain and blood sugar level increase. Sold by Pfizer Inc., ziprasidone is on the market in many countries, and accepted as a first-choice drug in its class according to guidelines for the treatment of mental disorders in the United States.

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