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- 5-HT4 Partial Agonist
| Compound Code | RQ-00000009 |
|---|---|
| Primary Target Indications | Alzheimer's disease |
| Development Stage | Phase 1 Portfolio for global development, manufacturing, and marketing rights |
| Product Summary | It is believed that the 5-HT4 receptor agonist can contribute to Alheimer's disease treatment by promoting the release of acetylcholine from nerve cells and by controlling the metabolism of amyloid precursor peptides. RQ-9 is a 5-HT4 receptor partial agonist, which is potent, highly selective and can penetrate the central nervous system. In Phase 1, we have confirmed its tolerability, safety and pharmacokinetics. |
| Non-Confidential Materials |
| Compound Code | RQ-00000010 |
|---|---|
| Primary Target Indications | Gastro-esophageal reflux disease |
| Development Stage | Pre-clinical trials Portfolio for global development, manufacturing, and marketing rights |
| Product Summary | RQ-10 is a potent 5-HT4 partial agonist, and it has the potential to be an innovative drug for GERD treatment that eliminates heart/vascular risks. In animal models it has exhibited a strong effect. |
| Non-Confidential Materials |

